In casual conversation, not really. The answer to the question of "What's your major?" or "What program are you in?" are the same.
In the finest technical definition, a major is taking a certain number of credit hours (possibly including some specific courses) in a subject area as part of a degree that works with majors - typically B.A. and B.Sc. degrees, where your degree winds up being "Bachelor of Science with major in Chemistry". For many other types of degrees, like Engineering, Computer Science (if it's not under a B.Sc. or B.A.), Business, etc. there is no technical concept of a major. And some schools use the terms like "Specialist" or "Specialization" to define something slightly different from a major (usually a bit more specialized, requiring some more courses in the subject area), in which case, again, you wouldn't technically have a major, you might have a "Bachelor of Science with specialization in Organic Chemistry".
So, in some cases, there could be a difference between a chemistry major and a chemistry specialist, or some other circumstances where there's different options available, while both would be chemistry programs, but if someone asked you what your major was you'd probably just say chemistry.
Remember that it often takes just as long to do a search or two on Google to try and find the answer to your question as it takes to type it in a post here, let alone the time waiting for a reply.
If your question is "What mark does it take to get into University X", or "What are the requirements to get into University X", it's on their website and/or
electronicinfo.ca (for Ontario schools). Particularly for Ontario schools, those ranges are a pretty good picture of what kind of mark will get you into the program, and if you're more than a couple percent higher it's practically guaranteed unless it requires a supplementary form.
